Male infertility – A Bitter Reality

Editor Review by : Alex Sam

Without knowing the exact cause behind the story every time women’s are blamed for infertility and are usually cursed and torched for the cause which she is not responsible for. This evil deed is practiced in the countries like India.

Today science has evidences for this cause and has proved that infertility may also be related to the men. Investigations has resulted that not only women can face the problem of infertility, but men can also lead to abnormalities of semen quality. The doctors usually advice both among the couple to seek check ups.

The hypothalamus is ultimately responsible for the reproductive disorder, as hypothalamus influences the production and secretion of gonadotrophin hormone. Gonadotrophin hormone is hormone secreted by the anterior pituitary gland and placenta; stimulates the gonads and controls reproductive activity.

Gonadotrophin hormone is released by hypothalamus that provokes the secretion and liberates both the luteinizing hormone and follicle stimulating hormone. These hormones are produced in the anterior of the pituitary glands and are secreted alternatively. These then ultimately bind to the specific receptors on the Leydig cells and Sertoli cells within the testis.

The luteinizing hormone is inhibited by the hormone testosterone which is produced by the testis. This testosterone may produce in the peripheral tissue ultimately to stimulate androgen dihydrotestosterone or the potent estrogen estradiol. Sertoli cells produce the Inhibin that directs the feed back mechanism and ultimately controls the production of follicle stimulating hormone.

Study shows that the concentration of spermatogenesis decreases with low level of inhibin and consequently results in decline in follicle stimulating hormone. Another type of hormone known as prolactin is also related with the gonadotropin releasing hormone, luteinizing hormone and follicle stimulating hormone. This prolactin accompany with hyperprolactinemia, inhibits the production of gonadotropin releasing hormone.

Unfortunately there were misbelieves that infertility is related with the women and those were ill-treated in the society. But science reached the peak to find out the alternative solution to this critical problem. Some advanced technology includes inseminations or IVF using donor sperm, and even genetic engineering proving blessing for such couples.